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Clopidogrel-treated patients with reduced function CYP219 variants experience reduced platelet inhibition and higher rates of adverse cardiovascular events ...

May 16, 2012 ... Expiration of the clopidogrel patent draws a close to a.

Plavix® (clopidogrel bisulfate) may help reduce risk of a future heart attack or stroke in patients with recent heart attack, recent stroke, heart-related chest pain ...

Clopidogrel is a pro-drug that requires oxidation to its active metabolite, 2- oxoclopidogrel, by CYP3A4 and other CYP enzymes. This active thiol metabolite ...

JAMA. 2011 Mar 16;305(11):1097-105. doi: 10.1001/jama.2011.290. Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous ...

Dec 28, 2011 ... Clopidogrel is an antiplatelet drug used by approximately 40 million patients worldwide1- 2 to treat or prevent atherothrombotic events and after ...

Clopidogrel is essential for the prevention of vascular events in patients after percutaneous coronary interventions (PCI). Most of our current knowledge with ...

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